Verified Analytical Catalog (2026)

Evidence-Based Peptide Science & Protocol Registry

An authoritative reference registry for research peptides. Explore comprehensive molecular dossiers, clinical outcome tables, reconstitution math, peer-reviewed PubMed citations, and price-per-milligram tracking.

Browse All Peptides 💧 Bacteriostatic Water Guide ⚡ Syringe Reconstitution Tool ⚖️ Head-to-Head Comparisons 🔬 Tested Vendor Rankings

Core Research Peptides Directory

Select any peptide to examine clinical trials, molecular structure, reconstitution ratios, and PubMed references.

28 VERIFIED COMPOUNDS
Metabolic & Fat Loss Approx. 6 days (144 hours)

Retatrutide

Next-generation single-peptide triple agonist targeting GLP-1, GIP, and Glucagon receptors, demonstrating unmatched body weight reduction and hepatic fat clearance in Phase 2 clinical trials.

🔬 Target Mechanism: Activates GLP-1 (satiety, insulin secretion), GIP (metabolic lipid buffering, in...
🏛️ PubChem CID: 171548842 ↗
Metabolic & Fat Loss Approx. 5 days

Tirzepatide

Dual GIP and GLP-1 receptor agonist engineered with a 39-amino acid modified sequence and C20 fatty diacid moiety that delivers profound metabolic control and fat loss.

🔬 Target Mechanism: Synergistically stimulates GIP and GLP-1 receptors, enhancing glucose-dependent ...
🏛️ PubChem CID: 16135400 ↗
Metabolic & Fat Loss Approx. 7 days (168 hours)

Semaglutide

Long-acting GLP-1 receptor agonist with 94% homology to human GLP-1, featuring albumin-binding fatty acid chain for once-weekly metabolic enhancement and appetite suppression.

🔬 Target Mechanism: Selectively binds GLP-1 receptors in the hypothalamus and brainstem, slowing gas...
🏛️ PubChem CID: 56843331 ↗
Metabolic & Fat Loss Approx. 7-8 days

Cagrilintide

Long-acting synthetic amylin analogue acylated for once-weekly subcutaneous dosing; works via distinct non-GLP neural pathways to trigger powerful early satiety and delayed gastric emptying.

🔬 Target Mechanism: Acts as a dual amylin and calcitonin receptor agonist (AMYR/CTR) in the area pos...
🏛️ PubChem CID: 162031264 ↗
Metabolic & Fat Loss Approx. 30 minutes

AOD-9604

Modified C-terminal fragment of human Growth Hormone (hGH 177-191) with an added tyrosine, specifically stimulating lipolysis and inhibiting lipogenesis without affecting IGF-1 or blood glucose.

🔬 Target Mechanism: Stimulates beta-3 adrenergic receptor pathways in adipose tissue, triggering the...
🏛️ PubChem CID: 13711 ↗
Metabolic & Fat Loss Approx. 4 hours in circulation; cellular epigenetic effects persist for days

MOTS-c

Mitochondrial-derived peptide encoded in the 12S rRNA that regulates metabolic homeostasis, activates AMPK, reverses insulin resistance, and acts as a profound exercise-mimetic.

🔬 Target Mechanism: Translocates to the nucleus under metabolic stress to regulate nuclear gene expr...
🏛️ PubChem CID: 138139589 ↗
Metabolic & Fat Loss Approx. 6 - 8 hours

5-Amino-1MQ

Small molecule / peptide-adjacent oral compound that selectively inhibits Nicotinamide N-methyltransferase (NNMT), revitalizing cellular metabolism and accelerating adipocyte shrinkage.

🔬 Target Mechanism: Inhibits NNMT enzyme in adipose and muscle tissues, increasing intracellular NAD...
🏛️ PubChem CID: 162464 ↗
Healing & Tissue Repair Approx. 4 hours (systemic biochemical cascades last 24+ hours)

BPC-157

Synthetic 15-amino acid peptide derived from human gastric juice protein, celebrated for systemic angiogenic, tendon, ligament, gut mucosa, and neuroprotective regenerative properties.

🔬 Target Mechanism: Upregulates VEGFR2, promotes FAK-paxillin angiogenesis pathway, stimulates early...
🏛️ PubChem CID: 16132283 ↗
Healing & Tissue Repair Systemic half-life ~24 hours; tissue actin-binding effects endure for multiple days

TB-500 (Thymosin Beta-4)

Synthetic fraction of the naturally occurring 43-amino acid protein Thymosin Beta-4 that sequesters actin, promotes cell migration, reduces fibrosis, and accelerates systemic tissue healing.

🔬 Target Mechanism: Binds and upregulates G-actin, facilitating cell motility and repair factor migr...
🏛️ PubChem CID: 16132341 ↗
Healing & Tissue Repair Approx. 1 - 2 hours in circulation; cellular gene-reprogramming effects persist for weeks

GHK-Cu (Copper Peptide)

Naturally occurring human tripeptide with high affinity for copper(II) ions, renowned for resetting gene expression to a younger state, boosting collagen/elastin synthesis, and reversing fibrosis.

🔬 Target Mechanism: Modulates over 4,000 human genes, upregulating collagen, elastin, proteoglycans,...
🏛️ PubChem CID: 73587 ↗
Healing & Tissue Repair Approx. 20 - 30 minutes (tissue receptor signaling triggers long-term repair)

ARA-290 (Cibinetide)

11-amino acid peptide derived from erythropoietin (EPO) that selectively activates the Innate Repair Receptor (IRR) without stimulating erythropoiesis, reversing small fiber neuropathy and neuropathic pain.

🔬 Target Mechanism: Selectively binds the tissue-protective erythropoietin receptor / CD131 heterodi...
🏛️ PubChem CID: 91826629 ↗
Healing & Tissue Repair Approx. 2 hours

KPV

Naturally occurring C-terminal tripeptide fragment of alpha-Melanocyte-Stimulating Hormone (alpha-MSH) with potent anti-inflammatory, antimicrobial, and gut barrier restorative actions without pigment changes.

🔬 Target Mechanism: Enters the cell nucleus to directly inhibit NF-kappaB translocation and downregu...
🏛️ PubChem CID: 122178 ↗
Growth Hormone Secretagogue Approx. 30 minutes (compared to 5-10 mins for native Sermorelin)

CJC-1295 (No DAC) / Mod GRF 1-29

Tetrasubstituted 29-amino acid GHRH analog engineered for enhanced metabolic stability, inducing natural pulsatile Growth Hormone and IGF-1 secretion without desensitizing receptors.

🔬 Target Mechanism: Binds GHRH receptors on pituitary somatotropes, triggering natural physiological...
🏛️ PubChem CID: 91826956 ↗
Growth Hormone Secretagogue Approx. 2 hours

Ipamorelin

Third-generation selective ghrelin receptor (GHSR-1a) agonist pentapeptide that stimulates pure Growth Hormone release without raising prolactin, cortisol, aldosterone, or appetite.

🔬 Target Mechanism: Selectively binds pituitary GHSR-1a receptors, triggering a robust, clean releas...
🏛️ PubChem CID: 9831659 ↗
Growth Hormone Secretagogue Approx. 26 - 38 minutes

Tesamorelin

Stabilized synthetic GHRH analog with a trans-3-hexenoyl group that potently reduces visceral adipose tissue (VAT) and improves lipid and cognitive profiles.

🔬 Target Mechanism: Acts on pituitary GHRH receptors to drive the synthesis and secretion of endogen...
🏛️ PubChem CID: 16137828 ↗
Growth Hormone Secretagogue Approx. 10 - 15 minutes

Sermorelin

Bioidentical 29-amino acid functional fragment of human Growth Hormone-Releasing Hormone, restoring natural pituitary pulsatility and vitality with an outstanding clinical safety history.

🔬 Target Mechanism: Directly stimulates the pituitary gland to produce and secrete growth hormone na...
🏛️ PubChem CID: 16132446 ↗
Growth Hormone Secretagogue Approx. 20 - 30 hours (compared to 15 mins for native IGF-1)

IGF-1 LR3

Recombinant 83-amino acid analog of human IGF-1 modified with an Arg substitution and 13-amino acid N-terminal extension that drastically lowers binding to inhibitory IGFBPs, resulting in extraordinary potency.

🔬 Target Mechanism: Binds with high affinity to the IGF-1 receptor and insulin receptor hybrids; byp...
🏛️ PubChem CID: 16131447 ↗
Longevity & Cellular Health Short serum half-life (~1 hour); epigenetic and telomeric upregulation persists for months

Epithalon (Epitalon)

Synthetic tetrapeptide based on pineal gland extract that activates telomerase, elongates telomeres, normalizes circadian rhythms, and extends healthy biological lifespan in mammalian studies.

🔬 Target Mechanism: Binds histone proteins to trigger epigenetic chromatin unraveling, reactivates t...
🏛️ PubChem CID: 21921319 ↗
Longevity & Cellular Health Approx. 4 hours

SS-31 (Elamipretide)

Mitochondria-targeting tetrapeptide that selectively binds cardiolipin in the inner mitochondrial membrane, restoring electron transport efficiency, reducing ROS, and rejuvenating aged bioenergetics.

🔬 Target Mechanism: Penetrates directly into the inner mitochondrial membrane to bind and stabilize ...
🏛️ PubChem CID: 11764719 ↗
Longevity & Cellular Health Extended stability due to all D-amino acid backbone resistance to proteases

FOXO4-DRI

D-retro-inverso peptide that disrupts the FOXO4-p53 interaction specifically in senescent "zombie" cells, triggering targeted apoptosis of senescent cells while leaving healthy cells completely unharmed.

🔬 Target Mechanism: Selectively interferes with the FOXO4-p53 complex in senescent cells; causes p53...
🏛️ PubChem CID: 139591410 ↗
Nootropic & Cognitive Approx. 20 - 30 minutes in blood; neurochemical elevation of BDNF/TrkB persists for 24+ hours

Semax

Synthetic Russian-developed heptapeptide analog of adrenocorticotropic hormone (ACTH 4-10) with potent BDNF upregulation, cognitive enhancement, ADHD symptom relief, and neuroprotective properties.

🔬 Target Mechanism: Boosts Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) mR...
🏛️ PubChem CID: 3034285 ↗
Nootropic & Cognitive Approx. 20 - 30 minutes; anxiolytic GABA-ergic modulation persists throughout the day

Selank

Synthetic heptapeptide analog of the human immunomodulatory peptide Tuftsin, engineered as a powerful non-sedating anxiolytic, mood enhancer, and immune-cognitive booster.

🔬 Target Mechanism: Modulates allosteric GABA-A receptors, stabilizes enkephalins by inhibiting enke...
🏛️ PubChem CID: 11765600 ↗
Nootropic & Cognitive Approx. 12 days biological effect / high metabolic resilience

Dihexa

Oligopeptide-derived small molecule with extraordinary neurogenic potency, facilitating synaptogenesis and Hepatocyte Growth Factor (HGF) activation at seven orders of magnitude greater than BDNF.

🔬 Target Mechanism: High-affinity binder to Hepatocyte Growth Factor (HGF), potentiating its dimeriz...
🏛️ PubChem CID: 24847953 ↗
Cosmetic & Skin Approx. 1 - 2 hours (biological skin melanin upregulation lasts weeks)

Melanotan II

Synthetic cyclic heptapeptide analog of alpha-MSH that stimulates melanin production (eumelanin) for deep sunless skin tanning while simultaneously activating central sexual libido pathways.

🔬 Target Mechanism: Non-selective melanocortin receptor agonist (MC1R for skin eumelanin production,...
🏛️ PubChem CID: 92432 ↗
Sexual & Hormonal Health Approx. 2.7 hours (sexual responsiveness lasts 8 - 14 hours)

PT-141 (Bremelanotide)

FDA-approved synthetic cyclic heptapeptide that acts centrally on the central nervous system to treat hypoactive sexual desire disorder (HSDD) and erectile dysfunction without vascular strain.

🔬 Target Mechanism: Acts as a central melanocortin MC4R and MC3R agonist in the medial preoptic area...
🏛️ PubChem CID: 9941379 ↗
Sexual & Hormonal Health Approx. 25 - 30 minutes (biological endocrine pulse triggers lasting cascade)

Kisspeptin-10

Endogenous decapeptide that governs the hypothalamic-pituitary-gonadal (HPG) axis, triggering natural GnRH, LH, and FSH release to restore endogenous testosterone and fertility.

🔬 Target Mechanism: Binds G-protein coupled receptor GPR54 (KISS1R) on hypothalamic GnRH neurons, st...
🏛️ PubChem CID: 10442581 ↗
Immune & Anti-Inflammatory Approx. 2 hours in blood; immune cell transcription shifts endure for days

Thymosin Alpha-1

Naturally occurring 28-amino acid thymic peptide that restores immune equilibrium, boosts T-cell and Natural Killer (NK) cell activity, fights chronic viral pathogens, and prevents immune exhaustion.

🔬 Target Mechanism: Interacts with Toll-like receptors (TLR2, TLR9) on dendritic cells and macrophag...
🏛️ PubChem CID: 16130571 ↗
Immune & Anti-Inflammatory Approx. 1 - 2 hours (membrane disruption is immediate on contact)

LL-37 (Cathelicidin)

Human antimicrobial peptide with broad-spectrum bactericidal, antiviral, and antifungal efficacy, capable of disrupting stubborn pathogenic bacterial biofilms.

🔬 Target Mechanism: Forms amphipathic alpha-helices that electrostatically bind negative bacterial c...
🏛️ PubChem CID: 388834920 ↗